A) Ovarian Stimulation

Under normal circumstances, most women produce only one egg each month. The chances of pregnancy are increased if more than one egg is fertilised and replaced. To increase the number of eggs, hormone injections (hormones to cause “down-regulation”, eg Buserilin, Lucrin; then FSH hormone to increase numbers of eggs developed, eg Gonal F) are administered daily. The most commonly used regime involves daily injections of Buserelin or Lucrin, usually commencing 21 days after your period starts (called the “down-regulation” regime). This hormone is first given to control your cycle by preventing your own hormones from disturbing egg production during the programme. Women may come to the Clinic every day for their injections, but as the needles used are very small, most women find it easier to learn how to give the injections themselves at home, or get their husbands to do it. This has the advantage that it saves you from coming to the hospital every day.  After two weeks of these injections, your response is monitored by a blood test and ultrasound scan. If these show you have responded to the Buserelin or Lucrin injections and the scan shows no abnormalities, a second hormone FSH is added, called Gonal F. This is designed to stimulate the ovaries to produce many eggs. The exact dose of the Gonal F injections may be varied according to your response, but the nurse and doctors will decide and let you know of any changes.

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